Ankylosing Spondylitis and the Spondyloarthropathies: A by Michael H. Weisman MD, John D. Reveille, Desiree van der

By Michael H. Weisman MD, John D. Reveille, Desiree van der Heijde

Built as a significant other textual content to the third variation of the heralded Rheumatology, by means of Hochberg et al., this cutting-edge reference provides modern day figuring out of the spondylarthropathies. you can find thorough examinations of the cutting edge, new remedies that problem older ideas of remedy and administration of the affliction. famous specialists within the box additionally current the most recent suggestions in early analysis utilizing complex imaging strategies * state of the art wisdom of the pathogenetic and epidemiologic positive aspects * crucial new advancements in immunology * and the newest realizing of the socio-demographic effect of the disease.Describes cutting edge therapy and administration innovations that assist you to supply sufferers with gigantic relief in discomfort, morbidity, and the extra dire effects of the sickness. allows speedy connection with the disease's actual manifestations via complete insurance of its scientific elements. lets you confirm the efficacy of organic brokers in keeping with the most recent insights on new remedies, together with anti-TNF. Assesses the advantages and boundaries of obtainable imaging modalities within the analysis and administration of spondylarthropathies.

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Extra info for Ankylosing Spondylitis and the Spondyloarthropathies: A Companion to Rheumatology 3E

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Diversity of alleles encoding HLA-B40: relative frequencies in United States populations and description of five novel alleles. Hum Immunol. 2000;61:808–815. 45. Robinson WP, van der Linden SM, Khan MA, et al. HLA-Bw60 increases susceptibility to ankylosing spondylitis in HLA-B27+ patients. Arthritis Rheum. 1989;32:1135–1141. 46. Rubin LA, Amos CI, Wade JA, et al. Investigating the genetic basis for ankylosing spondylitis. Linkage studies with the major histocompatibility complex region. Arthritis Rheum.

Steiner NK, Gans C, Baldassarre L, et al. Twenty-five novel HLA-B alleles. Tissue Antigens. 2003;62:263–266. 29. Ramos M, Lopez de Castro JA. HLA-B27 and the pathogenesis of spondyloarthritis. Tissue Antigens. 2002;60:191–205. 30. Boyle LH, Gaston JS. Breaking the rules: the unconventional recognition of HLA-B27 by CD4+ T lymphocytes as an insight into the pathogenesis of the spondyloarthropathies. Rheumatology (Oxford) 2003;42:404–412. 31. Boyle LH, Goodall JC, Opat SS, Gaston JS. The recognition of HLA-B27 by human CD4+ T lymphocytes.

Susceptibility to ankylosing spondylitis in twins: the role of genes, HLA, and the environment. Arthritis Rheum. 1997;40:1823–1828. 8. Porcher R, Said-Nahal R, D’Agostino MA, Miceli-Richard C, Dougados M, Breban M. Two major spondyloarthropathy phenotypes are distinguished by pattern analysis in multiplex families. Arthritis Rheum. 2005;53:263–271. 9. Ott J. Analysis of Human Genetic Linkage. Baltimore, Md: Johns Hopkins University Press; 1991. 10. Kelley J, Walter L, Trowsdale J. Comparative genomics of major histocompatibility complexes.

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