By Pavlidis, van Wyk.
We describe a style for inferring constraints which are fascinating for a given (rough) drawing after which editing the drawing to meet the restrictions anywhere attainable. the tactic has been applied as a part of an internet pics editor operating lower than the UNIX™ working method and it has gone through ameliorations in line with person enter. even supposing the framework we speak about is common, the present implementation is polygon-oriented. The family tested are: approximate equality of the slope or size of facets, collinearity of facets, and vertical and horizontal alignment of issues.
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However, more knowledge of both the cellular factors that influence cerebellar development, and optimal methods for altering these will be required, The long-term goal of this project is to establish methods to manipulate the cerebellum genetically. This will require both knowledge of the hierarchy of gene expression, and a capacity to deliver and control gene therapies. Experiments in this proposal will encompass both the underlying developmental neurobiology and vector technology to manipulate the genes.
The diagnostic and treatment methods advanced here are intended as a model to guide further development and implementation of more effective treatments for language disorders, particularly acquired dyslexia. ; Professor; Otolaryngology; University of Texas Hlth Sci Ctr Houston Box 20036 Houston, Tx 77225 Timing: Fiscal Year 2001; Project Start 30-SEP-2001; Project End 31-AUG-2005 Summary: (provided by applicant): This research will use an appropriate animal model to define the behavioral, physiological, and cellular changes that correlate with deficits in auditory temporal processing.
Several non-temporal controls (absolute thresholds, frequency and intensity discrimination) will prove the deficits are unique to rapidly changing sounds. Physiological recordings and immunohistochemistry of cells of the central auditory system will define possible mechanisms of the behavioral deficits. According to an important current hypothesis, difficulty processing the basic elements of language (phonemes) is due to a deficit in the perception of rapidly changing sounds. Basic questions about the early development of auditory temporal processing and the insults that can cause a decrement in these important abilities remain unanswered.