Bioinformatics: Converting Data to Knowledge, Workshop by Robert Pool

By Robert Pool

The objective of this workshop was once to collect bioinformatics stake holders from govt, academe, and for an afternoon of displays and discussion. Fifteen specialists pointed out and mentioned probably the most very important concerns raised through the present flood of biologic information. subject matters explored incorporated the significance of database curation, database integration and interoperability, consistency and criteria in terminology, errors prevention and correction, facts provenance, ontology, the significance of holding privateness, information mining, and the necessity for extra laptop scientists with uniqueness education in bioinformatics. even supposing formal conclusions and suggestions won't come from this actual workshop, many insights might be gleaned in regards to the way forward for this box, from the context of the discussions and shows defined here.

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The group also creates software tools and adds value to these Web resources via curation. The group is involved in various analyses of genomes and their gene products. The third major project is on DNA expression microarrays. It is working with Stanford laboratories on yeast, human, mouse, E. coli, C. elegans, and Arabidopsis microarrays. Dr. Cherry’s interests are in integrating and facilitating the analysis of the vast amounts of information in genome and microarray databases. *Susan B. Davidson is professor of Computer and Information Science and co-director of the Center for Bioinformatics at the University of Pennsylvania, where she has been since 1982.

Issues addressed in that domain include the resolution of semantic inconsistencies, effective delegation of processing to remote nodes, simulation for augmentation of results, and providing security and privacy in collaborative settings. His early research contributions included development of real-time data-acquisition technology for medical research (1966), time-oriented databases for ambulatory care (1972), the initiation of knowledge-based research (1977), and the concept of mediated architectures for information integration (1990).

Maintaining the Integrity of Databases D atabases can contain billions of bytes of information, so it is inevitable that some errors will creep in. Nonetheless, the researchers who work with databases would like to keep the errors to a minimum. Error prevention and correction must be integral parts of building and maintaining databases. The reasons for wanting to minimize errors are straightforward, said Chris Overton, director of the Center for Bioinformatics at the University of Pennsylvania.

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