By Arthur Lesk
Первое издание очень известного учебника, написанного Артуром Леском, профессором кафедры гематологии Кембриджского университета (Соединённое Королевство). Книга несколько раз переиздавалась. Последнее издание вышло в 2008 году.Раздачи по теме:
By James Tisdall
With its hugely built capability to discover styles in info, Perl has develop into probably the most renowned languages for organic info research. but when you're a biologist with very little programming adventure, beginning out in Perl could be a problem. Beginning Perl for Bioinformatics is designed to get you quick over the Perl language barrier through coming near near programming as a tremendous new laboratory ability, revealing Perl courses and methods which are instantly priceless within the lab. each one bankruptcy makes a speciality of fixing a selected bioinformatics challenge or category of difficulties, beginning with the best and lengthening in complexity because the e-book progresses. every one bankruptcy contains programming routines. by means of the top of the e-book you'll have an effective figuring out of Perl fundamentals, a suite of courses for such initiatives as parsing BLAST and GenBank, and the talents to tackle extra complex bioinformatics programming.
By Peter E. Nielsen
Peter Eigil Nielsen has assembled a significantly evaluated choice of key PNA protocols which are both already good confirmed all over the world, corresponding to PCR-clamping and in situ hybridization, or that exhibit promise of vital destiny effect. uncomplicated equipment for PNA oligomer synthesis and research have additionally been integrated. Written through specialists with hands-on within the tools they describe, those with no trouble reproducible protocols include distinctive step by step directions, pointers on keeping off pitfalls and on extending the strategy to different events, and introductory fabric explaining the idea at the back of the method.
By ERIC MARECHAL, Sylvaine Roy, Laurence Lafanechère
Biological and chemical sciences have gone through an extraordinary transformation, mirrored by way of the large use of parallel and automatic applied sciences in key fields equivalent to genome sequencing, DNA chips, nanoscale practical biology or combinatorial chemistry. it truly is now attainable to generate and shop from tens of millions to hundreds of thousands of recent small molecules, in keeping with more suitable chemical synthesis options. automatic screening of small molecules is likely one of the applied sciences that has revolutionized biology, first constructed for the pharmaceutical and lately brought in educational laboratories. High-throughput and high-content screening enable the id of bioactive compounds in collections of molecules (chemical libraries), being powerful on organic objectives outlined at a number of organisational scales, from proteins to cells to accomplish organisms. those bioactive molecules might be healing drug applicants, molecules for biotech, diagnostic or agronomic functions, or instruments for easy learn. dealing with quite a few organic (genomic and post-genomic), chemical and experimental info, screening methods can't be envisaged with none digital garage and mathematical therapy of the information. “Chemogenomics and Chemical Genetics" is an introductory guide proposing tools and ideas making up the foundation for this contemporary discipline.
This booklet is devoted to biologists, chemists and desktop scientist novices. it truly is equipped briefly, illustrated chapters with useful examples. transparent definitions of billogical, chemical and IT techniques are given in a thesaurus part to aid readers who're now not conversant in this sort of disciplines. "Chemogenomics and Chemical Genetics" may still for that reason be necessary for college students (from Bachelor's measure level), technological platform engineers, and researchers in biology, chemistry, bioinformatics, cheminformatics, either in biotech and educational laboratories.
By Natalie Kuldell, Neal Lerner
The technology of biology celebrates the invention and figuring out of organic structures that exist already in nature. In parallel, the engineering of biology needs to the right way to utilize our realizing of the flora and fauna to layout and construct new valuable organic structures. "Synthetic biology" represents one instance of modern paintings to engineer organic platforms. This rising box goals to switch the advert hoc technique of assembling organic structures through essentially constructing instruments to collect reliable-but-complex residing organisms from ordinary elements that could later be reused in new blend. the focal point of this booklet is "genome refactoring," among the many ways to control the complexity of a organic approach within which the target is to revamp the genetic parts that encode a residing form--preserving the functionality of that shape yet encoding it with a genome some distance more uncomplicated to check and expand. This booklet provides genome refactoring in methods: as a big point of the rising box of artificial biology and as a robust instructing instrument to coach will be pros within the topic. Chapters specialize in the overarching ambitions of man-made biology and their alignment with the motivations and achievements in genome engineering; the engineering frameworks of refactoring, together with genome synthesis, standardization of organic elements, and abstraction; a close description of the bacteriophages which were refactored as much as this element; and the tools of refactoring and contexts for that paintings drawn from the bacteriophage M13. total, those examples supply readers the possibility of artificial biology and the parts wanting extra learn. If profitable, artificial biology and genome refactoring may tackle any variety of continual societal wishes, together with sustainable power, cheap and powerful drugs, and eco-friendly production practices. desk of Contents: instruments for Genome Engineering and artificial Biology / Bacteriophage as Templates for Refactoring / Methods/Teaching Protocols for M13 Reengineering / Writing and conversing as organic Engineers / precis and destiny instructions / Appendix A / Appendix B / Appendix C
By Charlie Hodgman, Andrew French, David Westhead
The second one variation of fast Notes in Bioinformatics brought the readers to the subjects and terminology of bioinformatics. it really is divided into 3 elements: the 1st being an advent to bioinformatics in biology; the second one masking the actual, mathematical, statistical and computational foundation of bioinformatics, utilizing organic examples anyplace attainable; the 3rd describing functions, giving particular aspect and together with info criteria. The purposes coated are series research and annotation, transcriptomics, proteomics, metabolite examine, supramolecular association, structures biology and the mixing of-omic facts, body structure, picture research, and textual content research.
By Anna-Lena Lamprecht (auth.), Anna-Lena Lamprecht (eds.)
The non-stop development in machine technology to raise programming to raised abstraction degrees raises scalability and opens programming to a much broader public. particularly, service-oriented programming and the aid of semantics-based frameworks make program improvement available to clients with nearly no programming services. This monograph establishes requirement-centric medical workflow layout as an example of consequent constraint-driven improvement. necessities formulated by way of user-level constraints are immediately remodeled into operating purposes utilizing temporal logic-based synthesis know-how. The influence of this process is illustrated by way of employing it to 4 very diversified bioinformatics situations: phylogenetic research, the committed GeneFisher-P state of affairs, the FiatFlux-P situation, and microarray information analyses.
By Jonathan Pevsner
The bestselling advent to bioinformatics and genomics – now in its 3rd edition
Widely bought in its prior variants, Bioinformatics and useful Genomics bargains the main broad-based creation to this explosive new self-discipline. Now in a completely up to date and improved 3rd version, it is still the go-to resource for college students and execs interested in biomedical research.
This ebook presents up to date insurance of the fields of bioinformatics and genomics. positive aspects new to this version include:
- Extensive revisions and a moderate reorder of chapters for a more desirable organization
- A fresh bankruptcy on next-generation sequencing
- An extended spouse web site, additionally up-to-date as and whilst new details turns into available
- Greater emphasis on a computational technique, with transparent suggestions of the way software program instruments paintings and introductions to using command-line instruments similar to software program for next-generation series research, the R programming language, and NCBI seek utilities
The ebook is complemented by way of lavish illustrations and greater than 500 figures and tables - many newly-created for the 3rd variation to augment readability and knowing. each one bankruptcy contains studying goals, an issue set, pitfalls part, packing containers explaining key strategies and mathematics/statistics ideas, a precis, instructed studying, and an inventory of freely to be had software program. Readers may perhaps stopover at a similar website for supplemental details corresponding to PowerPoints and audiovisual documents of lectures, and videocasts of the way to accomplish many simple operations: www.wiley.com/go/pevsnerbioinformatics.
Bioinformatics and useful Genomics, 3rd version serves as a good single-source textbook for complex undergraduate and starting graduate-level classes within the organic sciences and machine sciences. it's also an fundamental source for biologists in a huge number of disciplines who use the instruments of bioinformatics and genomics to review specific study difficulties; bioinformaticists and computing device scientists who boost desktop algorithms and databases; and clinical researchers and clinicians who are looking to comprehend the genomic foundation of viral, bacterial, parasitic, or different diseases.
By Nicholas Wright Gillham
This readable review covers the increase of clinical genetics in the course of the prior century, and the eugenic impulses it has encouraged. Nicholas Gillham studies the linkages among genes and disorder; ethnic teams’ differential susceptibility to genetic characteristics and problems; custom-made medication; and an important social and moral matters coming up from the field’s growth.