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Read or Download Clinical Depression - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References PDF
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Extra info for Clinical Depression - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References
We will parametrically manipulate attentional enhancements during pursuit tracking to clarify the causes of what appears to be a reduced influence of extra retinal signals on the control of pursuit eye movements in schizophrenia. We will use an oculomotor delayed response (ODR) task to study spatial working memory impairments in schizophrenia. We will parametrically manipulate the rate of "distractor" information presented during the delay period of this prototypic spatial working memory task in order to model changes in dorsal brain regions of interest across a range of processing load conditions.
Does improving rates of use of efficacious treatment improve outcomes, and at what costs? To address this question, we propose a randomized trial at the clinic level to evaluate an intervention featuring patient and primary care-provider education about treatment for depression, coupled with clinic resources that facilitate initiation and provision of appropriate care, whether medication management or full-course Cognitive Behavioral Therapy. We assess intervention effects, compared to care as usual, on quality of care, satisfaction with care, clinical symptoms and daily functioning, service use and costs, and indirect costs and parental psychological distress.
We are currently funded by the NIGMS, Pharmacogenetic Research Network and Knowledge Base (UO1GM6 1394) to conduct a one-year pilot study on the pharmacogenetics of depression in Mexican-Americans. This renewal application was designed to expand that effort from a pilot study to a full proposal that brings together a crossdisciplinary group of highly accomplished experts in order to create a unique pharmacogenetics resource for the Mexican-American community. Our accomplishments in the first three months of pilot funding demonstrate the feasibility of our program of research.