Coenzyme Q: Molecular mechanisms in health and disease by Kagan V., Quinn P. (eds.)

By Kagan V., Quinn P. (eds.)

Due to the fact its discovery in 1957, Coenzyme Q has piqued the curiosity of scientists from quite a lot of disciplines as a result of its bioenergetics, vitamin-like habit, and interactions with antioxidant supplements E and C. Coenzyme Q: Molecular Mechanisms in overall healthiness and disorder is a entire treatise in this often-studied coenzyme. overseas specialists disguise the study that resulted in its emergence as an exhilarating, new nutritional supplement.The current quantity summarizes the newest advancements in quite a few parts of CoQ study. New suggestions on extramitochondrial services of CoQ are mentioned in chapters, whereas fresh discoveries in biosynthetic pathways for CoQ in line with molecular genetic methods are offered in one other chapter.Further chapters discover the function of CoQ as an antioxidant, revealing the necessity for extra examine during this interesting sector. This ebook should be of maximum curiosity to biochemists, biophysicists, molecular and mobile biologists, in addition to nutritionists and biomedical medical experts.

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The data concerning the folded conformation of CoQ homologs are partly taken from the experimental thesis by F. Andriani (July 1999). REFERENCES 1. Crane, F. , Isolation of a quinone from beef heart mitochondria, Biochim. Biophys. Acta, 1000, 358, 1989. 2. Crane, F. L. , The diversity of coenzyme Q function, Molec. , 8, s1–s6, 1997. 3. Beyer, R. , The role of ascorbate in antioxidant protection in biomembranes. Interaction with vitamin E and Coenzyme Q, J. Bioenerg. , 26, 349, 1994. 4. Ernster, L.

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Gomez-Fernandez, J. , Llamas, M. , and Aranda, F. , The interaction of coenzyme Q with phosphatidylethanolamine membranes, Eur. J. , 259, 739, 1999. 62. , Determination of partition and lateral diffusion coefficients of ubiquinones by fluorescence quenching of n-(9-anthroyloxy)stearic acids in phospholipid vesicles and mitochondrial membranes, Biochemistry, 25, 3378, 1986. 63. , Synthesis, location, and lateral mobility of fluorescently labeled ubiquinone 10 in mitochondrial and artificial membranes, Biochemistry, 28, 3168, 1989.

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